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In melanoma, downregulation of IGF-1 reduces the dry character of melanoma initiating cells, including the expression of dry markers (SOX2, Oct-3/4, CD24 and CD133) and functional properties (melanosphere formation, aldehyde dehydrogenase activity and side population) and eventually inhibiting the proliferation and metastasis of tumor cells (26)

Krishnan S, Anderson MP, Fields DA, Misra M

Archibald, Multimodal Nanoparticle Imaging Agents: Design and Applications

loaded tobramycin (Tb) into CTS-NPs and poly (vinyl alcohol)-alginate/PLGA-NPs and converted them into dry powders by SD

Additionally, IFN- also upregulates ACSL4 and influences the lipid profiles of tumor cells, promoting the synthesis of arachidonic acid-PLs [145]

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